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Acute kidney injury Experimental studies Ischemic acute kidney injury (AKI) in rodents and humans results in preferential damage of the distal segment of the proximal tubule (S 3 -segment) and the thick ascending limb of the loop of Henle, indicated by loss of brush borders, cell necrosis and apoptosis, since this part of the nephron heavily depends on medullary blood flow in order to preserve oxygen supply [179]

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2.4.4.3 Chromatographic conditions Chromatographic column: ACQUITY UPLC HSS T3 (100 mm2.1 mm, 1.8 um)

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Potential Effects of Orally Ingesting Polyethylene Terephthalate Microplastics on the Mouse Heart